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Automatic Highspeed Vertical Ampoule Filling & Sealing Machine
Ampoule Filling Machine ₹2,275,000.00
Automatic Ampoule Filling & Sealing Machines
Precision, sterility, and high-speed performance are the hallmarks of the Harsiddh Unimach ampoule filling range. Our machines are engineered to provide a seamless, hermetic sealing solution for the pharmaceutical and biotech industries. Designed to handle glass ampoules with extreme care, our equipment integrates filling and sealing into a single, synchronized process that minimizes human intervention and maximizes product integrity.
Our Ampoule Filling Range
- Automatic 2-Head Ampoule Filling & Sealing Machine: Perfect for R&D labs and pilot-scale production, offering precision in a compact footprint.
- Automatic 4-Head Ampoule Filling & Sealing Machine: A versatile, mid-range solution for scaling pharmaceutical operations.
- Automatic 6-Head & 8-Head High-Speed Machines: High-capacity systems designed for 24/7 industrial production, reaching speeds of up to 18,000 ampoules per hour.
Salient Features
- cGMP Compliant Build: All contact parts are made of SS 316L, with the main structure in SS 304, ensuring easy sterilization and long-term durability.
- Draw-off Sealing Technology: Utilizes the superior “draw-off” method for a smooth, rounded, and leak-proof seal, eliminating the sharp edges common in tip-sealing.
- Nitrogen Flushing System: Integrated pre-and-post filling nitrogen gas purging to protect oxygen-sensitive liquids and extend product shelf life.
- Centering at Filling Station: Precise ampoule neck centering during the filling operation to prevent liquid from touching the sealing area, which ensures a clean, carbon-free seal.
- “No Ampoule – No Filling” System: Smart sensor logic prevents the filling pump from operating if an ampoule is missing, reducing waste and mess.
- Minimum Changeover Time: Designed for rapid switching between 1ml to 10ml ampoule sizes with minimal tool requirements.
- Synchronized Drive: All stations—from feeding and nitrogen flushing to filling and sealing—are perfectly synchronized via a single-point drive for consistent accuracy.
Frequently Asked Questions
How does the machine ensure the sterility of the liquid during the filling process?
To maintain strict pharmaceutical hygiene, Harsiddh Unimach machines are built with SS 316L contact parts and follow cGMP standards. The machines include integrated Nitrogen Flushing units that purge the ampoule before and after filling to remove oxygen, preventing oxidation and ensuring product stability.
What is the difference between a 2-head, 4-head, and 8-head ampoule filler?
The primary difference is the production output.
- 2-Head: Ideal for R&D or small batches (approx. 30–50 BPM).
- 4-Head: Suitable for medium-scale production (approx. 70–100 BPM).
- 8-Head: Designed for high-speed industrial lines, reaching up to 12,000–18,000 ampoules per hour.
What sealing method is used, and is a gas supply required?
The machines utilize the "Draw-off Sealing" method, which provides a superior, rounded finish compared to tip-sealing. It requires a combination of LPG and Oxygen gases to create the high-temperature flame necessary to melt the glass neck before the mechanical grippers pull away the waste tip.
How is the filling accuracy maintained across thousands of cycles?
Accuracy is controlled via high-precision volumetric syringes (piston pumps). The stroke length is easily adjustable to fine-tune the fill volume. Additionally, our machines feature a "No Ampoule – No Filling" sensor system, which ensures that the filling pump only activates when a container is correctly positioned, preventing spillage and maintaining a clean environment.
