Automatic Crushable Ampoule Filling & Sealing Machine
Exclusive AUTOMATIC CRUSHABLE AMPOULE FILLING & SEALING MACHINE introduced by Harsiddh including onion skin tube (OST) filling machine & glass tube filling machine. The contact parts of this filler sealer are made of AISI 316L grade stainless steel with a customized single motor that complies with all different major unit drives. This crushable ampoule filling machine possesses both post & pre nitrogen flushing units and also operates the mechanism of nitrogen-flushing. Another benefit of this filling machine is the need of minimum ampoule/tubes changes. Our CE certified crushable ampoule filling machines also have an active pre-heating unit suitable for thick glass ampoules.
Crushable Ampoule Filling Machine
This range of filler and sealer machine includes onion skin tube filler sealer machine & crushable glass tube filler sealer machine has the capacity to fill and seal glass tubes up to the capacity of 10ml. With the help of this crushable ampoule filling and sealing machine has a capacity of filling material from 0.1 – 10 ml in single doses. This crushable ampoule filling machine has a production capacity from 10-100 glass tubes per minute when operated on the principle of volumetric piston-pumps / peristaltic pump type filling. Apart from that, this filling machine has a sleep tray available that offers a proper division of filled and sealed glass tubes or crushable ampoules.
In this crushable ampoule filling machine, Oxygen & LPG are the required gases for the purpose of filling and sealing crushable ampoules. This first-class crushable ampoule filler sealer machine offers the maximum flexibility needed during the production of glass tubes accommodating veterinary medicines, agro-insecticides, and various other chemicals. Complete range including biological indicator filling machine, crushable ampoule filling machine, OST filling machine and various other such filler and sealer machines are available with Harsiddh that are suitable for all different kinds of glass tubes / crushable ampoules.
Technical Specification
| Model No. | HFS-30 OST / HFS-55 OST / HFS-4 OST (Suitable For Onion Skin Tubes / Crushable Ampoules / Biological Indicator) |
| No. Of Head | One / Two / Four Heads |
| Size Of Onion Skin Tubes / Crushable Ampoules / Biological Indicators | Dia. 6mm to 15mm Length – 55mm to 100mm Or as per customer size |
| Filling Capacity | From 0.5ml to 5ml in single dose |
| Filling Type | Peristaltic Pumps Type Filling |
| Filling accuracy | +1% |
| Contact Parts | Stainless Steel AISI 316L (For Filling Nozzles) |
| Filling Head | One / Two / Four |
| Sealing Nozzle | One / Two / Four |
| Output / Minute | 10 to 100 Tubes / Minute (Depend on models) |
| Require Gases For Sealing | LPG & Oxygen (Mixture) |
| Nitrogen Purging | Available (Pre & Post) |
| Pre Heating | Available |
| Power Require | 0.5/1 H.P., 220 Volts, 1 Phase, 50 Hz OR Customized |
| Over All Dimensions | Depend on model |
| Net Weight | Depend on model |
| Gross Weight (With Wooden Case) | Depend on model |
Frequently Asked Questions
How does the machine handle such fragile glass without breakage?
Since crushable ampoules are engineered with extremely thin glass walls, the Harsiddh machine uses a Synchronized Walking Beam or Rotary Transport System. This mechanism minimizes glass-to-metal contact and utilizes soft-touch grippers or "star-wheels" made of medical-grade engineering plastics. This ensures that the ampoules are moved through the filling and sealing stations with zero mechanical stress.
What filling technology is used for micro-volume liquid dosing?
To ensure the accuracy required for diagnostic reagents, the machine is equipped with a Micro-Filling System, typically utilizing Peristaltic Pumps or Valveless Ceramic Pistons. These systems provide a dosing accuracy of ±0.5% to 1%, which is essential for the consistency of the chemical reaction when the ampoule is eventually crushed by the end-user.
How is the "Tip Sealing" process managed to protect the contents?
The machine uses a precision Oxygen-LPG Flame Sealing system. After filling, the ampoule neck is pre-heated and then "tip-sealed" by a specialized burner. To protect heat-sensitive reagents or biological spores inside the ampoule, the machine is designed with a Heat-Sink Cooling System or nitrogen flushing to maintain a stable temperature at the base of the ampoule while the top is being melted shut.
What are the key construction and compliance features of the machine?
As a cGMP-compliant model, the Harsiddh Crushable Ampoule machine is built for cleanroom environments:
Material: All contact parts are made of SS 316L, while the main structure is SS 304 stainless steel.
Automation: Managed by a centralized PLC with a Touchscreen HMI, allowing for precise control over flame temperature, filling speed, and conveyor timing.
Safety: Features a "No Ampoule – No Fill" sensor to prevent liquid wastage and an integrated exhaust system to safely remove combustion gases from the sealing flame.
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